SAMe

Jarrow FORMULAS® pharmaceutical grade; stabilized SAM-e 200 provides a full 200 mg SAM-e (net yield) from 400 mg of SAM-e tosylate disulfate. SAM-e 200 is manufactured under low temperature and low humidity and is enteric-coated to ensure a biologically active product. 

Contains More of the Active S;S Form

Found in all living cells; SAM-e is a metabolite of methionine (an essential amino acid). SAM-e is a chiral molecule and consists of two forms: (S;S) SAM-e and (R;S) SAM-e. The biologically active form is the (S;S) structure; while the (R;S) structure is biologically inactive. Jarrow FORMULAS® SAM-e is made naturally by microbiological fermentation and then specially processed without solvents to preserve 68-80% (S;S) SAM-e; the highest active level available.

SAM-e has been clinically shown to have the following benefits:

• Joint Strength
• SAM-e supports the production of healthy connective tissue through transulfuration.  In this process; critical components of connective tissue; including glucosamine and the chondroitin sulfates; are sulfated by SAM-e metabolites.*
• Brain Metabolism
• SAM-e methylation reactions are involved in the synthesis of neurotransmitters such as L-DOPA; dopamine and related hormones; serotonin; epinephrine and phosphatidylcholine (a component of lecithin).*
• Longevity
• Methylation of DNA appears to be important in the suppression of errors in DNA replication. Demethylation of DNA is considered a contributor to the aging process.* Proper methylation through substances such as SAM-e positively influences longevity.*
• Liver
• SAM-e metabolism supports the synthesis of glutathione (GSH) and glutathione-dependent enzymes (glutathione peroxidase and glutathione-S-transferase); which are substances important for liver function.*
• Made in the USA

Jarrow FORMULAS® pharmaceutical grade; stabilized SAM-e 400 provides a full 400 mg SAM-e (net yield) from 800 mg of SAM-e tosylate disulfate. SAM-e 400 is manufactured under low temperature and low humidity and is enteric-coated to ensure a biologically active product.

Contains More of the Active S;S Form

Found in all living cells; SAM-e is a metabolite of methionine (an essential amino acid). SAM-e is a chiral molecule and consists of two forms: (S;S) SAM-e and (R;S) SAM-e. The biologically active form is the (S;S) structure; while the (R;S) structure is biologically inactive. Jarrow FORMULAS® SAM-e is made naturally by microbiological fermentation and then specially processed without solvents to preserve 68-80% (S;S) SAM-e; the highest active level available.

SAM-e has been clinically shown to have the following benefits:

• Joint Strength 
• SAM-e supports the production of healthy connective tissue through transulfuration. In this process; critical components of connective tissue; including glucosamine and the chondroitin sulfates; are sulfated by SAM-e metabolites.*
• Brain Metabolism
• SAM-e methylation reactions are involved in the synthesis of neurotransmitters such as L-DOPA; dopamine and related hormones; serotonin; epinephrine and phosphatidylcholine (a component of lecithin).*
• Longevity
• Methylation of DNA appears to be important in the suppression of errors in DNA replication. Demethylation of DNA is considered a contributor to the aging process. Proper methylation through substances such as SAM-e positively influences longevity.*
• Liver
• SAM-e metabolism supports the synthesis of glutathione (GSH) and glutathione-dependent enzymes (glutathione peroxidase and glutathione-S-transferase); which are substances important for liver function.*
• PRODUCT OF ITALY